Latest Publications
Below is a sampling of recent publications attesting to the growing need for high dimensional single-cell technologies within precision drug development and some successful applications to date.
The Single-Cell Pathology Landscape of Breast Cancer
Single-cell analyses have revealed extensive heterogeneity between and within human tumours 1–4 , but complex single-cell phenotypes and their spatial context are not at present reflected in the histological stratification that is the foundation of [...]
Multispectral Imaging Enables Characterization of Intrahepatic Macrophages in Patients With Chronic Liver Disease
Congratulations to our Scientific Advisory Board Chairman, Jared K. Burks, on co-authoring an insightful piece on multispectral imaging of various chronic liver diseases, including NASH! Jared and his collaborators across the UT Health System continue [...]
B Cells and Tertiary Lymphoid Structures Promote Immunotherapy Response
Treatment with immune checkpoint blockade (ICB) has revolutionized cancer therapy. Until now, predictive biomarkers1–10 and strategies to augment clinical response have largely focused on the T cell compartment. However, other immune subsets may also contribute [...]
